Symptoms of endometriosis

As we have already noted, in some cases, especially at the beginning, the pathology can proceed without pronounced signs and when using  https://pillintrip.com/medicine/tachidol.

The main symptoms of endometriosis in women include:

Pelvic pain. It occurs in 15-25% of patients. Unpleasant sensations can be both local and diffuse throughout the pelvis. In some cases, they increase only before menstruation. Usually pain is provoked by an inflammatory process that develops in the affected organs.
Menstruation flowing with severe discomfort. This symptom of endometriosis is diagnosed in 40-60% of women. Pain usually occurs in the first few days of menstruation.
Painful intercourse.

Also, the signs of pathology include:

Computer illustration showing the female reproductive system, including the bladder, uterus and ovaries. The endometrium (lining of the uterus) is extending outside the uterus, into the fallopian tube, ovary and abdominal cavity, in a disease called endometriosis. It causes intense pain in the pelvic region.

Prolonged and heavy menstruation.
Discomfort during urination and defecation.
Development of anemia (due to intense blood loss).
Almost half of women are diagnosed with infertility. Experts in the field of gynecology have not yet been able to identify the cause of its occurrence in endometriosis. Most likely, reproductive function is affected by changes that occur in the tubes and ovaries due to tissue growth. Also, violations of ovulation, local and general immunity, which are the result of pathology, can lead to the impossibility of conception.

Arthrosis of the knee joint

Arthrosis (osteoarthritis) of the knee joint is a disease in which the cartilage in the knee gradually becomes thinner. This usually results in chronic knee pain. In this disease it is allowed to use https://pillintrip.com/medicine/postafen-meclozine to treat other diseases.

Symptoms of the disease:

Pain – there is pain in the knee;
Rigidity – if you do not move the knee for a long time, it seems rigid;
Softness – the knee feels soft when you put pressure on it;
Loss of flexibility – the knee is more difficult to move;
Popping – there may be a feeling that the knee is “popping”;
Knee protrusions – small bony protrusions may form around the affected joint;
Swelling – The knee is swollen.

For treatment, you can prescribe:

Paracetamol – pain reliever to relieve pain;
Non-steroidal anti-inflammatory drugs – help relieve pain;
Duloxetine is also used to relieve pain.

A patient with arthrosis is also prescribed physiotherapy, during which he

Woman having knee pain in medical office

performs exercises that reduce pain in the joint and increase its mobility. It also helps with weight loss. In addition, occupational therapy is used, when the patient is taught to reduce the load on the joint in everyday life. For example, put a chair in the shower so as not to stand while washing. This reduces stress on the knee.

If treatment and therapy do not help, surgery is performed:

Cortisone injections – cortisone, a substance that relieves pain and swelling, is injected into the joint;
Osteotomy – the bone is cut and rebuilt so that the load on the bone goes differently;
Joint replacement – the damaged part of the bone is removed and a prosthesis is put in its place.

What if I have Covid-19?

Every day my acquaintances contact me with different symptoms of ARVI:

– “Can I have a crown?” ⠀

Yes maybe. Now a pandemic of coronavirus infection, the symptoms of which differ little from ARVI. ⠀

“So, what are my actions? Calling an ambulance? Use https://pillintrip.com/ru/medicine/pedifen?” ⠀
To answer this question, you need a short questionnaire: ⠀
-Age? ⠀
-How are you feeling? ⠀
– Do you have chronic diseases? -Do you get any medication every day? ⠀
-Is it possible to isolate yourself from your family? Especially if there are pregnant women among them, people with severe background pathology, old people? ⠀

✔If you are young, feel good, breathe easily, live alone or have the possibility of isolation – stay at home for 14 days, treat symptoms

❗If after a week or earlier it becomes difficult to breathe, chest pain, weakness appear, urgently call an ambulance. ⠀

➡In all other cases, the doctor’s consultation is needed to determine the strategy: stay at home, be hospitalized, adjust the baseline, add drugs, etc. Why not immediately an ambulance? Do they do tests, prescribe treatment, I’m calmer, won’t we start the disease?

🔴Fast uploaded ⠀
🔴doctors face the infected, they can become a source of infection themselves ⠀
🔴You can become a source of infection for the doctor ⠀

And all why ⠀
❌ There is no effective treatment. Inpatient therapy is aimed at relieving symptoms, in particular oxygen supply due to lung damage. ⠀
❌We are not yet able to prevent a severe course. There is no vaccine, no preventive treatment. ⠀
❌We do not yet know why some people have a difficult disease, while others are asymptomatic. Age and chronic pathology are important. That’s all. ⠀

How can we help ourselves❓ ⠀
☀Sport ⠀
☀vitamins (# vit D) ⠀
☀full nutrition ⠀
😉 good attitude: remember, this is temporary, you need to go through it, everything will be over soon, and by this moment we must be mentally safe! ⠀
💉Continue vaccination. It’s okay if your deadlines are violated. We deliver what you need (excl: rotatek up to 32 weeks) ⠀
💊Continue basic therapy, for example, BA (ICS, montelukast NOT ⬆ chances of getting sick, but obstruction ➕ to 👑 will worsen the prognosis due to existing inflammation) ⠀

🕛Take off asthma attacks in time. If you can’t cope, see a doctor
What you don’t need to do:

Try to treat something: soda, alcohol by mouth or inhalation (dangerous! Can cause severe cough, obstruction),

Purchase drugs included in the hospital treatment protocols (chloroquine, plaquenil, etc.). They have side effects, it is dangerous to take it on their own, the effect is

Any amount of alcohol consumption is bad for the brain

A British study found that there is no safe amount of alcohol and vimax for the brain, and even “moderate” drinking has a negative effect on almost all parts of it.

The more alcohol consumed, the smaller the consumer’s brain volume, the researchers found. “Apparently, almost the entire brain is affected, not just some of its areas, as previously thought,” explains lead researcher and senior clinical professor at the University of Oxford, Anya Topiwala.

Using an extensive British biobank database, the researchers analyzed data from 25,378 participants, including parameters such as age, gender, education, alcohol consumption, brain size and health on MRI scans, hospital admissions and outpatient visits, and psychological memory tests.

Higher weekly alcohol consumption was associated with lower gray matter density – researchers found that alcohol explains up to 0.8% of the change in gray matter volume, even after adjusting for individual biological and behavioral characteristics. This may sound like a small figure, but this contribution is greater than any other modifiable risk factors. For example, this is four times the contribution of smoking or being overweight.

Negative links have also been seen between alcohol consumption and the integrity of the white matter, the many fibers in the brain that connect the billions of neurons that make up the gray matter of the brain, the main “thinking organ” of humans. In addition, the researchers found that other risk factors, such as high blood pressure and high body mass index, exacerbate the negative association between alcohol and brain health.

Unlike previous studies that suggested there were benefits to drinking wine in moderation compared to beer or spirits, this study found no evidence that the type of alcoholic beverage determines any difference in brain risks. …

In 2016, the UK Department of Health set a low alcohol risk limit for both men and women at 14 standard units of alcohol per week. But it turned out that the damage to the brain is associated with much smaller amounts of alcoholic beverages.

Anxiety and fear, panic, panic moods

Anxiety and fear can cause panic and panic moods. But they may not if you are in control of your states.

Anxiety and fear as feelings arise when a person loses control over his or her own life and behavior, loses un

derstanding of how to live and act here (in the present) and now or there and then (in the future).

It is important to unders

tand that in most cases a person can cope with them, regain a sense of control himself/herself or with the help of other people. The mechanism of fear consists in the fact that the person loses the supports of his or her own behavior, state and well-being. This can occur both subjectively and objectively.

For example, if a person finds himself in an absolutely dark room – he loses visual supports and cannot move, understanding that any step may be fraught with trauma. This is an objective loss of support. Fear of getting hurt or experiencing pain completes the picture and completely defines the behavior: the person cannot move.

What happens next? The person turns on the “non-standard” reserve systems of perception and orientation – hearing, sense of smell, touch, different “sixth” and “seventh” senses. They make it possible to assess the situation and act. But what will happen if all these “reserve systems” also fail or fail to work? Yes, panic will “turn on”.

Inadequate reactions in the dark room will mean that all the systems of perception and evaluation of the situation do not work and the person turns on the “hyperreaction” – as when running away from a great danger – running away from the danger and dangerous situation without noticing anything.

Panic, unlike fear, is not a feeling, but a type of reaction – a chaotic, disorderly reaction with an almost complete loss of control over behavior.

Anxiety and fear during an epidemic are normal reactions to a serious and unusual problem, to a situation of uncertainty. In such a situation, people often produce a hypertrophied “adaptation reaction” – they begin to obsessively watch the news, read material about the disease, discuss it with acquaintances and draw dramatic pictures of the future.

In order to cope with such states on one’s own, we offer several simple techniques. You can also ask your doctor to prescribe this medicine: https://pillintrip.com/medicine/azor-anti-anxiety.


Find five objects of different colors around you and examine them
Feel four sensations in your body (touch of hand and armrest, foot and floor, etc.)
Hear 3 sounds in the environment (or hear 3 instruments in a melody)
Smell 2 smells
Feel 1 taste sensation

Practice attentive deep breathing.
Breathe in through the nose slowly
Hold breath for 4 to 5 seconds
Exhale slowly through the mouth with the teeth closed, creating a slight tension to the exhaled air.


How does the ingredient of the drug work? You can read about it here: https://pillintrip.com/medicine/fungoral. The active ingredient damages the outer shell, the so-called cell membrane of fungi. This envelope thus loses some of its functions, becoming more impermeable to nutrients, for example – the cell starves. Depending on the concentration of the active ingredient, the fungi are thus inhibited in their growth and reproduction, or they die directly due to additional damage to the cell interior.

Application guidelines

The total dose should not be exceeded without consulting a doctor or pharmacist.Method of use?Rub the medicine into the scalp.Or: rub the medicine onto the affected skin area(s).Beforehand, moisten the affected area(s) with water. The medicine should stay on the skin for 3-5 minutes. Then rinse it off with plenty of warm water. Avoid accidental contact with the eyes.Duration of use?For seborrheic dermatitis: 2-4 weeks, for prophylaxis every 2nd week for 12 weeks to a maximum of 6 months; for skin rash caused by fungus of bran: maximum 5 days. Without medical advice, do not use the drug for longer than 2 weeks if there is no improvement of symptoms after this time.Overdose?If the drug is used as described, no overdose symptoms are known. If in doubt, consult your doctor.Forgotten to use?Continue use at the next prescribed time as normal (i.e., do not double the amount).In general, be sure to use a conscientious dosage, especially with infants, young children, and the elderly. If in doubt, ask your doctor or pharmacist about any effects or precautions.A dosage prescribed by a doctor may differ from the information in the package leaflet. Since the doctor adjusts it individually, you should therefore use the drug according to his instructions.


What are the contraindications to use?- Hypersensitivity to the ingredientsWhat about pregnancy and breastfeeding?- Pregnancy: consult your doctor. Several considerations play a role in whether and how the drug can be used during pregnancy.- Lactation: The drug should not be applied to the breast.If you have been prescribed the drug despite a contraindication, talk to your doctor or pharmacist. The therapeutic benefit may be higher than the risk associated with the use in case of contraindication.

Important Notes

What should you be aware of?
– The drug must not be discontinued prematurely, otherwise a (new) outbreak of the disease can be expected.
– Caution in case of allergy to antifungal agents (e.g. clotrimazole)!
– Caution in case of allergy to formaldehyde (E number E 239)!

What is Betamethasone (Frenaler Cort)?

Betamethasone (Frenaler Cort) sodium phosphate and Betamethasone (Frenaler Cort) acetate combination injection provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, lung or breathing problems, blood or bone marrow problems, eye or vision problems, lupus, serious skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis. Betamethasone (Frenaler Cort) sodium phosphate and Betamethasone (Frenaler Cort) acetate combination is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

Betamethasone (Frenaler Cort) sodium phosphate and Betamethasone (Frenaler Cort) acetate is to be given only by or under the direct supervision of your doctor.

Betamethasone (Frenaler Cort) Suspension is indicated for the treatment of acute and chronic corticosteroid-responsive disorders. Corticosteroid hormone therapy is an adjunct to, and not a replacement for conventional therapy.

Musculoskeletal and Soft Tissue Conditions: Rheumatoid arthritis, osteoarthritis, bursitis, ankylosing spondylitis, epicondylitis, radiculitis, coccydynia, sciatica, lumbago, torticollis, ganglion cyst, exostasis and fasciitis.

Allergic Conditions: Chronic bronchial asthma (including adjunctive therapy for status asthmaticus), hay fever, angioneurotic edema, allergic bronchitis, seasonal or perennial allergic rhinitis, drug reactions, serum sickness and insect bites.

Dermatologic Conditions: Atopic dermatitis (nummular eczema), neurodermatitis (circumscribed lichen simplex), contact dermatitis, severe solar dermatitis, urticaria, hypertrophic lichen planus, necrobiosis lipoidica diabeticorum, alopecia areata, discoid lupus erythematosus, psoriasis, keloids, pemphigus, dermatitis herpetiformis and cystic acne.

Collagen Diseases: Disseminated lupus erythematosus, scleroderma, dermatomyositis, periarteritis nodosa.

Neoplastic Diseases: Palliative management of leukemias and lymphomas in adults; acute leukemia of childhood.

Other Conditions: Adrenogenital syndrome, ulcerative colitis, regional ileitis, sprue, podiatric conditions (bursitis under heloma durum, hallux rigidus, digiti quinti varus), affections requiring subconjunctival injection, corticosteroid-responsive blood dyscrasias, nephritis and nephrotic syndrome.

Frenaler Cort sodium phosphate and Betamethasone
Frenaler Cort sodium phosphate and Betamethasone

Primary or secondary adrenocortical insufficiency may be treated with Betamethasone (Frenaler Cort) Suspension but should be supplemented with mineralocorticosteroids, if applicable.

Betamethasone (Frenaler Cort) Suspension is recommended for intramuscular injection in conditions responsive to systemic corticosteroids; injection directly into the affected soft tissues where indicated; intra-articular and periarticular injection in arthritides; intralesional injection in various dermatologic conditions; and local injection in certain inflammatory and cystic disorders of the foot.


Use Betamethasone (Frenaler Cort) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Betamethasone (Frenaler Cort) by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Use the dropper that comes with Betamethasone (Frenaler Cort) to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If Betamethasone (Frenaler Cort) needs to be stopped (or if a different medicine is added to therapy) by your doctor, this will be done gradually. The risk of side effects may be increased if Betamethasone (Frenaler Cort) is suddenly stopped.
  • If you miss a dose of Betamethasone (Frenaler Cort), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Betamethasone (Frenaler Cort).

This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Betamethasone (Frenaler Cort) reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a medium-strength corticosteroid.

How to use Betamethasone (Frenaler Cort) topical

Use this medication on the skin only. However, do not use it on the face, groin, or underarms unless directed to do so by your doctor.

Wash and dry your hands before using. Clean and dry the affected area. Apply a thin film of medication to the affected area and gently rub in, usually 1-3 times daily or as directed by your doctor. Do not bandage, cover, or wrap the area unless directed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.

After applying the medication, wash your hands unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma. Also, avoid getting this medication in the nose or mouth. If you get the medication in these areas, rinse with plenty of water.

Use this medication only for the condition for which it was prescribed. Do not use it for longer than prescribed.

Inform your doctor if your condition persists or worsens after 2 weeks.

Each gram of Betamethasone (Frenaler Cort) (Betamethasone (Frenaler Cort)*) Cream* contains: 640 mcg Betamethasone (Frenaler Cort) dipropionate (equivalent to 500 mcg Betamethasone (Frenaler Cort)).

Each gram of Betamethasone (Frenaler Cort) (Betamethasone (Frenaler Cort)*) Ointment* contains: 640 mcg Betamethasone (Frenaler Cort) dipropionate (equivalent to 500 mcg Betamethasone (Frenaler Cort)).

Betamethasone (Frenaler Cort) (Betamethasone (Frenaler Cort)*) Cream and Ointment contain Betamethasone (Frenaler Cort) dipropionate, a synthetic corticosteroid with anti-inflammatory activity to be administered topically.

Betamethasone (Frenaler Cort) dipropionate is a white to creamy white odorless crystalline powder insoluble in water; freely soluble in acetone and in chloroform; sparingly soluble in alcohol. It has a molecular weight of 504.16 and the empirical formula C28H37FO7; a chemical name of 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione,17,21-dipropionate.


Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Kit, Injection:

Pod-Care 100C: Betamethasone (Frenaler Cort) sodium phosphate 3 mg and Betamethasone (Frenaler Cort) acetate 3 mg per 1 mL [contains benzalkonium chloride, disodium edta]

ReadySharp Betamethasone (Frenaler Cort): Betamethasone (Frenaler Cort) sodium phosphate 3 mg and Betamethasone (Frenaler Cort) acetate 3 mg per 1 mL [contains benzalkonium chloride, disodium edta]

Suspension, Injection:

Betamethasone (Frenaler Cort): Betamethasone (Frenaler Cort) sodium phosphate 3 mg and Betamethasone (Frenaler Cort) acetate 3 mg per 1 mL (5 mL) [contains benzalkonium chloride, edetate disodium]

Generic: Betamethasone (Frenaler Cort) sodium phosphate 3 mg and Betamethasone (Frenaler Cort) acetate 3 mg per 1 mL (5 mL)

Dosing: Adult

Note: Dosages expressed as combined amount of Betamethasone (Frenaler Cort) sodium phosphate and Betamethasone (Frenaler Cort) acetate; 1 mg is equivalent to Betamethasone (Frenaler Cort) sodium phosphate 0.5 mg and Betamethasone (Frenaler Cort) acetate 0.5 mg.

Usual dosage range: IM: Initial: 0.25 to 9 mg/day (based on severity of disease and patient response).

Indication-specific dosing:

Antenatal fetal maturation (off-label use): IM: 12 mg every 24 hours for a total of 2 doses (ACOG 171 2016). A single course of Betamethasone (Frenaler Cort) is recommended for women between 24 and 34 weeks of gestation, including those with ruptured membranes or multiple gestations, who are at risk of delivering within 7 days. A single course may be appropriate in some women beginning at 23 weeks gestation or late preterm (between 34 0/7 weeks and 36 6/7 weeks gestation). A single repeat course may be considered in some women with pregnancies less than 34 weeks gestation at risk for delivery within 7 days and who had a course of antenatal corticosteroids >14 days prior (ACOG 171 2016; ACOG 713 2017, ACOG 188 2018).

Bursitis (other than of foot): Intra-articular: 3 to 6 mg (0.5 to 1 mL) for one dose; additional injections may be required for acute exacerbations or chronic conditions; generally, injections should be separated by a minimum of 4 to 6 weeks and limited to ≤4 injections per year. If symptoms are not improved after 1 or 2 injections, additional injections are unlikely to provide benefit (Cardone 2002); following resolution of acute episodes, reduced doses may be warranted for chronic conditions.

Dermatologic conditions: Intradermal: 1.2 mg/cm displayed a good or excellent response (Chowdri, 1994). Another trial (n=25, age range: 7 weeks to 2 years) used lower doses of 3 to 12 mg (in combination with triamcinolone); 16 patients experienced a marked response (Kushner, 1985).

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Polygot is a migraine medicine

Polygot – tablets (coated) containing caffeine 0.1 g and ergotamine tartrate 0.001 g (1 mg). Polygot is used for migraine (vasoparalytic form), as well as a drug that lowers intracranial pressure in vascular, traumatic, infectious lesions of the central nervous system. The effect is due to the vasoconstrictor effect of ergotamine and improvement of cerebral function under the influence of caffeine.

Polygot is a migraine medicine

It is prescribed orally on 1-2 tablets per intake during a headache attack 2 times a day, then 1 tablet 2-3 times a day for several days (up to 1 month). After oral administration, about 62% of ergotamine is absorbed in the gastrointestinal tract. Maximum plasma concentrations are achieved 2 hours after oral administration. Binding to plasma proteins is 98%. Ergotamine is metabolized in the liver to form pharmacologically active metabolites. Ergotamine is excreted mainly with bile both unchanged and as metabolites. Excretion is biphasic, with half-lives of 2.7 hours and 21 hours for I and II phases, respectively. After oral administration caffeine is absorbed quickly and almost completely. Binding with plasma proteins is 35%. Caffeine is almost completely metabolized in the body. Metabolites are excreted mainly with urine. The elimination half-life is about 3.5 hours.

Polygot is a migraine medicine

One of the most common forms of headache is migraine, which affects about 13% of the population in the world, mainly women. Migraine is a very severe disease and represents a significant burden to society and, above all, to patients who suffer from frequent attacks of headache. Unlike many other types of headache, migraine is characterized by predominantly severe attacks with severe disadaptation, impaired ability to work and daily functioning. According to data of a large-scale study of the American Migraine Study II, on the days of attacks, about 53% of patients completely lose the ability to work. On average, each migraine patient loses 3.2 working days per year. The proportion of patients who have to continue working at the time of a headache attack has a more than 46% reduction in work activity. Therefore, the vast majority of patients (about 80%) have to take pain medication during almost every attack. It is for this reason that migraine headaches are the fourth most frequent reason for seeking emergency care, accounting for 1-3% of all cases. This is often due not only to severe, prolonged, or poorly manageable headaches, but also to the many unusual, difficult-to-tolerate symptoms that almost always accompany migraine pain.

There are two main strategies for treating migraine: migraine attack control and prophylactic treatment. The goals of preventive treatment are to reduce the frequency, intensity and duration of attacks, to reduce the need for headache medication, and to increase adaptation and daily functioning. Prophylactic treatment is not indicated for all patients, but only for those who suffer from frequent attacks or attacks that are accompanied by severe disadaptation, and in cases when patients themselves prefer preventive treatment. In contrast, attack control is necessary for virtually all patients, both those who have frequent attacks and those who have infrequent attacks. The goal of migraine attack control is to eliminate the headache and associated symptoms, and to prevent the possibility of pain recurrence.

Sarcoidosis – lung disease

Systemic lung disease, characterized by the formation of granules in the lung tissue, is accompanied by cough, chest pain, weakness, fever.
Sarcoidosis is a more frequent disease than is commonly thought. The incidence of sarcoidosis in the world ranges from 11 to 640 per 100,000 people. The disease develops at any age, even after 70 years, but the peak of sarcoidosis is 40 years. It was believed that women suffer from sarcoidosis more often than men. However, apparently, it is not so: women simply have more pronounced symptoms of the disease, which means they are more likely to see doctors.

The cause of sarcoidosis is unknown, so there is still no exhaustive definition of the disease. The main finding is sarcoid granulomas (epithelioid cell granulomas without caseosal necrosis).


Sarcoidosis - lung disease

In more than 90% of cases, the lungs or intra-thoracic lymph nodes are affected, but there are no complaints, at least not at an early stage. Even with extensive lung damage (chest X-ray) there may be no breathlessness or coughing. Dyspnea and other complaints usually occur at an advanced stage of the disease.

The first manifestation of sarcoidosis may be eye damage. Iridocyclitis, chorioiditis, conjunctivitis and lacrimal gland affection with xerophthalmia (dry eyes) are noted in 25% of cases. Approximately 20% of patients have the first sarcoidosis: plaques from orange-pink to brown color. Approximately 10% of patients suffer from the nervous system. Sarcoidosis may be suspected of impaired pituitary function or hypercalcemia (increased calcium levels). In addition, manifestations of sarcoidosis are hepatosplenomegaly (increase in the liver and spleen), bone damage (more often phalanges of the fingers) and symmetrical lesions of the joints. Significant pathology of the heart is rare, but in some cases there are violations of heart rhythm, cardiomyopathy. In 10% of patients, especially those with extensive affection of lymph nodes, there is a fever.


The stages of sarcoidosis are determined from the data of chest X-ray.
Stage I: bilateral increase in bronchopulmonary lymph nodes.
Stage II: Bilateral enlargement of bronchopulmonary lymph nodes and diffuse lesions of the pulmonary parenchyma, reticular remodeling of the lung pattern, but sometimes multiple focal or biliary shadows.
Stage III: Affection of the pulmonary parenchyma without enlargement of bronchopulmonary lymph nodes.
The probability of spontaneous remission (self-recovery) at stages I, II and III is 80, 50 and 30% respectively.


Sarcoidosis - lung disease

In 90% of patients the disease is limited to lesions of the intra-thoracic lymph nodes and lungs and often runs asymptomatically. In such cases, radiological changes may be an accidental finding, for example, during a prophylactic examination or examination for another disease. As already mentioned, the first manifestation of sarcoidosis may be lesion of other organs. In any case, before making a diagnosis, the doctor must obtain histological confirmation of sarcoidosis.


Despite the fact that glucocorticoids have been used for over 45 years, there is still no consensus on the advisability of their treatment for lung sarcoidosis. Practice shows that glucocorticoid treatment is justified in all patients with stages II and III, if within 6-12 months there are no signs of spontaneous remission or there are signs of deterioration (according to radiography and examination of respiratory function). As a rule, taking 40 mg of prednisolone a day is sufficient.
Although some specialists recommend starting treatment only when there are complaints, studies have shown that shortness of breath appears in the irreversible phase of the disease. Therefore, it is better to prescribe glucocorticoids before complaints occur to prevent the development of irreversible changes.
Most specialists adhere to the following indications for prescription of glucocorticoids: 1) uveitis (begin with local treatment), 2) hypercalcemia, 3) myocardial damage (especially cardiomyopathy), 4) neurological disorders. If glucocorticoids are contraindicated for any reason, the following drugs are recommended: methotrexate, chloroquine, azathioprine and oxyphenbutazone.


Surveillance of sarcoidosis patients necessarily includes regular chest X-rays and examination of external respiration function (spirometry). The frequency of examination depends on the course of the disease, as well as the preferences of the attending physician. The course of sarcoidosis can be assessed by the activity of angiotensin-converting enzyme in the blood. The frequency of relapse after treatment of patients with stages II and III is about 25%. Therefore, at the end of treatment, patients should be monitored for several years. The probability of relapse is significantly reduced, if for more than a year the condition remains stable and there are no signs of sarcoidosis activity.

Lung diseases: important facts that need to be known

Medicine knows many diseases associated with our lungs and other respiratory system organs. Some of these diseases are chronic, some are fatal and some can be quickly treated. What should you know about lung diseases?

Lung diseases: important facts that need to be known

Medicine knows many diseases related to our lungs and other respiratory system, ranging from bronchitis, asthma of varying intensity, chronic lung disease, to deadly diseases – lung cancer and idiopathic pulmonary fibrosis. Some of these diseases are chronic, some are fatal, and some can be quickly treated.

As with the treatment of any other disease, the wrong diagnosis and improperly appointed treatment can lead to significant deterioration of health. Some of the respiratory illnesses are widespread, especially in the cold winter, while others are considered rare and poorly understood.

What is known about respiratory diseases?

Lung diseases: important facts that need to be known

The most common childhood disease is bronchial asthma. About 5%-10% of children suffer from severe chronic forms of asthma, which is characterized by severe inflammation of the respiratory tract and is accompanied by prolonged seizures of breathing difficulties.
Some of the lung diseases are chronic, and medicine still does not know the methods that would lead to their complete cure. However, recent medical research has led to the emergence of new drugs and treatments that can significantly improve patients’ quality of life. For example, a real breakthrough was the emergence of new drugs to treat pulmonary fibrosis. New drugs change the course of the disease, improve the quality of life of patients and help slow down the rate of deterioration. New drugs have also appeared against lung cancer.
Lung diseases may manifest themselves at a very early age. Chronic obstructive pulmonary disease is considered a disease of the elderly, and is usually diagnosed at the age of 50-60 years. But it is important to know that much of these diagnoses were made at a late stage, when the disease is already difficult to treat. The first symptoms of the disease may appear at the age of + 40 years.
The condition worsens in the cold season: most often the symptoms of respiratory illness are exacerbated in autumn and winter. In cold air promotes asthmatic reactions and breathing difficulties. This rule is common for almost all lung diseases.
Passive smoking can also cause respiratory diseases. For a long time, there was a widespread perception that only people who smoke are susceptible to respiratory diseases. Research shows that for a number of diseases (obstructive pulmonary disease, pulmonary fibrosis, and lung cancer), smoking remains a major development factor. But to date, it has been found that both the above diseases and other lung diseases can also be diagnosed in people who have never smoked in their lives, but are constantly in a smoking environment, being passive smokers.
There are products that provoke sputum and cough. In particular, we are talking about dairy products. Although there is still no consensus in the medical community on whether or not to avoid dairy products for patients with asthma or lung disease, the general recommendation remains to limit the daily diet of products that cause mucus and sputum. Such products include milk, citrus fruits, bananas, and peanuts.
Personal approach to the treatment of each patient is a very important component of therapy, especially today, when there are a variety of modern techniques and developments that can significantly improve the quality of life of patients with the most severe, chronic respiratory diseases. Medicines, including biological drugs, are selected strictly individually, so the use of drugs that are incompatible with the patient’s body can lead to serious complications.