It is now proven that chronic bronchitis develops in almost 100% of cases among smokers. Chronic inflammation may be accompanied by metaplasia of the epithelium, resulting in a decrease in the number of cells with eyelashes. With constant exposure to cigarette smoke may dysplasia epithelium, uthe development of malignant tumors.
In the clinic, exacerbations of the disease are combined with periods of remission. Most patients with chronic bronchitis develop pulmonary emphysema. Complications of chronic bronchitis are right ventricular failure and lung failure, so says Dr. Denis Slinkin.
Dr. Denis Slinkin will assert that in the early stages of the disease chronic bronchitis of infectious nature may initially have a local nature, there is inflammation of respiratory bronchitis with a diameter of less than 2 mm. Chronic inflammation may lead to destruction of the bronchial wall and surrounding elastin fibres, which leads to the development of centrolobular emphysema. Reduced air pressure and pliability of the bronchial walls, together with blockage of the lumen by slime, lead to significant difficulties in air passage through the airways. Chronic bronchitis and emphysema are usually observed simultaneously in different proportions